[JWBlue]

AFC

(4) Houston Texans at (1) Kansas City Chiefs
When: Saturday, 4:30 p.m. ET (ESPN/ABC/ESPN+)
FPI projection: KC, 62.4%
Opening line: KC -8 (42.5)

(3) Baltimore Ravens at (2) Buffalo Bills
When: ​Sunday, 6:30 p.m. ET (CBS/Paramount)
FPI projection: BAL & BUF, 50%
Opening line: BUF -1 (51.5)

NFC

(6) Washington Commanders at (1) Detroit Lions
When: Saturday, 8 p.m. ET (Fox)
FPI projection: DET, 72.2%
Opening line: DET -8.5 (54.5)

(4) Los Angeles Rams at (2) Philadelphia Eagles
When: Sunday, 3 p.m. ET (NBC/Peacock)